sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 1.000 | |
| 4b0i | KBP | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.654 | |
| 4b8u | IBK | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.560 | |
| 4b0j | 3MQ | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.550 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.471 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.465 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.460 | |
| 3wag | TYD | Glycosyltransferase | / | 0.456 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.452 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.452 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.450 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.448 | |
| 3lbe | COA | Uncharacterized protein | / | 0.447 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.446 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.441 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 |