sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3v9l | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3v9l | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 1.000 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.514 | |
| 4ihi | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.495 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.481 | |
| 3haz | NAD | Bifunctional protein PutA | / | 0.466 | |
| 4i1w | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.464 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.454 | |
| 3lns | NAP | NAD(P)-dependent benzaldehyde dehydrogenase | 1.2.1.28 | 0.454 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.453 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.450 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.446 | |
| 3iwk | NAD | Aminoaldehyde dehydrogenase | / | 0.445 | |
| 4pt3 | NDP | Aldehyde dehydrogenase | / | 0.445 | |
| 4zz7 | NAD | Methylmalonate-semialdehyde dehydrogenase | / | 0.445 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.442 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.440 |