sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3u8m	09R	Acetylcholine-binding protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3u8m	09R	Acetylcholine-binding protein	/	1.000
3u8k	09P	Acetylcholine-binding protein	/	0.618
3u8n	09S	Acetylcholine-binding protein	/	0.570
3zdg	XRX	Acetylcholine-binding protein	/	0.545
4alx	IZN	Acetylcholine-binding protein	/	0.505
3wip	ACH	Acetylcholine-binding protein	/	0.486
3wti	CT4	Acetylcholine-binding protein	/	0.449
3zdh	XRS	Acetylcholine-binding protein	/	0.444
2yyi	FAD	4-hydroxyphenylacetate 3-monooxygenase oxygenase component	1.14.14.9	0.442
3gwf	FAD	Cyclohexanone monooxygenase	/	0.441
4q71	FAD	Bifunctional protein PutA	/	0.440