sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3t8d	UBV	Thermolysin	3.4.24.27

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3t8d	UBV	Thermolysin	3.4.24.27	1.000
3t8h	UBS	Thermolysin	3.4.24.27	0.900
3t74	UBY	Thermolysin	3.4.24.27	0.802
4tln	LNO	Thermolysin	3.4.24.27	0.665
2tmn	0FA	Thermolysin	3.4.24.27	0.644
6tmn	0PI	Thermolysin	3.4.24.27	0.643
3t87	UBZ	Thermolysin	3.4.24.27	0.630
4tmn	0PK	Thermolysin	3.4.24.27	0.626
4h57	0PJ	Thermolysin	3.4.24.27	0.620
3t8c	UBW	Thermolysin	3.4.24.27	0.615
4d9w	X32	Thermolysin	3.4.24.27	0.615
1qf2	TI3	Thermolysin	3.4.24.27	0.586
3for	ZNP	Thermolysin	3.4.24.27	0.578
3fgd	BYA	Thermolysin	3.4.24.27	0.539
3f28	S7B	Thermolysin	3.4.24.27	0.471
4zr5	RDF	Neprilysin	/	0.470
4ara	C56	Acetylcholinesterase	3.1.1.7	0.441