sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3t74	UBY	Thermolysin	3.4.24.27

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3t74	UBY	Thermolysin	3.4.24.27	1.000
3t8h	UBS	Thermolysin	3.4.24.27	0.774
3t8d	UBV	Thermolysin	3.4.24.27	0.768
4tln	LNO	Thermolysin	3.4.24.27	0.656
4h57	0PJ	Thermolysin	3.4.24.27	0.607
1qf2	TI3	Thermolysin	3.4.24.27	0.606
6tmn	0PI	Thermolysin	3.4.24.27	0.606
4tmn	0PK	Thermolysin	3.4.24.27	0.596
2tmn	0FA	Thermolysin	3.4.24.27	0.593
3t8c	UBW	Thermolysin	3.4.24.27	0.590
3t87	UBZ	Thermolysin	3.4.24.27	0.581
4d9w	X32	Thermolysin	3.4.24.27	0.577
3for	ZNP	Thermolysin	3.4.24.27	0.550
3fgd	BYA	Thermolysin	3.4.24.27	0.483