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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3rahO1ZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3rahO1ZCyclin-dependent kinase 22.7.11.221.000
3r9nZ68Cyclin-dependent kinase 22.7.11.220.674
3r8vZ62Cyclin-dependent kinase 22.7.11.220.566
3lfnA27Cyclin-dependent kinase 22.7.11.220.502
1w8cN69Cyclin-dependent kinase 22.7.11.220.499
1e1xNW1Cyclin-dependent kinase 22.7.11.220.495
4fklCK2Cyclin-dependent kinase 22.7.11.220.492
3qtsX46Cyclin-dependent kinase 22.7.11.220.484
3r83Z14Cyclin-dependent kinase 22.7.11.220.476
3qwjX6ACyclin-dependent kinase 22.7.11.220.472
3r71X86Cyclin-dependent kinase 22.7.11.220.464
2c6o4SPCyclin-dependent kinase 22.7.11.220.463
3iggEFQCyclin-dependent kinase 22.7.11.220.462
3r7yZ04Cyclin-dependent kinase 22.7.11.220.462
4kd11QKCyclin-dependent kinase 22.7.11.220.462
3qzgX67Cyclin-dependent kinase 22.7.11.220.461
3wblPDYCyclin-dependent kinase 22.7.11.220.455
2c6lDT4Cyclin-dependent kinase 22.7.11.220.454
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.454
3rpo24ZCyclin-dependent kinase 22.7.11.220.450
2c69CT8Cyclin-dependent kinase 22.7.11.220.449
2exmZIPCyclin-dependent kinase 22.7.11.220.449
3r8lZ30Cyclin-dependent kinase 22.7.11.220.448
5aniES4Cyclin-dependent kinase 22.7.11.220.445
1pxmCK5Cyclin-dependent kinase 22.7.11.220.442
2c6kDT2Cyclin-dependent kinase 22.7.11.220.441
3rkb12ZCyclin-dependent kinase 22.7.11.220.440