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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3r8pZ46Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3r8pZ46Cyclin-dependent kinase 22.7.11.221.000
3r71X86Cyclin-dependent kinase 22.7.11.220.601
4kd11QKCyclin-dependent kinase 22.7.11.220.575
3r7yZ04Cyclin-dependent kinase 22.7.11.220.548
3rm618ZCyclin-dependent kinase 22.7.11.220.529
3iggEFQCyclin-dependent kinase 22.7.11.220.520
3rpo24ZCyclin-dependent kinase 22.7.11.220.512
1oitHDTCyclin-dependent kinase 22.7.11.220.509
3r83Z14Cyclin-dependent kinase 22.7.11.220.507
4ek816KCyclin-dependent kinase 22.7.11.220.503
3qruX19Cyclin-dependent kinase 22.7.11.220.490
3qwjX6ACyclin-dependent kinase 22.7.11.220.490
2c6o4SPCyclin-dependent kinase 22.7.11.220.488
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.486
3qqlX03Cyclin-dependent kinase 22.7.11.220.486
3lfnA27Cyclin-dependent kinase 22.7.11.220.483
3lfqA28Cyclin-dependent kinase 22.7.11.220.483
1oirHDYCyclin-dependent kinase 22.7.11.220.479
3rpv26ZCyclin-dependent kinase 22.7.11.220.478
1w8cN69Cyclin-dependent kinase 22.7.11.220.476
3r8lZ30Cyclin-dependent kinase 22.7.11.220.468
3r1sX73Cyclin-dependent kinase 22.7.11.220.464
3r1yX76Cyclin-dependent kinase 22.7.11.220.464
1y91CT9Cyclin-dependent kinase 22.7.11.220.463
3sqq99ZCyclin-dependent kinase 22.7.11.220.462
2r3q5SCCyclin-dependent kinase 22.7.11.220.460
3rak03ZCyclin-dependent kinase 22.7.11.220.460
4fki09KCyclin-dependent kinase 22.7.11.220.459
1w0xOLOCyclin-dependent kinase 22.7.11.220.458
2btrU73Cyclin-dependent kinase 22.7.11.220.457
2a0cCK9Cyclin-dependent kinase 22.7.11.220.456
1aq1STUCyclin-dependent kinase 22.7.11.220.454
3ezrEZRCyclin-dependent kinase 22.7.11.220.454
2exmZIPCyclin-dependent kinase 22.7.11.220.453
3r8vZ62Cyclin-dependent kinase 22.7.11.220.452
3rk708ZCyclin-dependent kinase 22.7.11.220.452
2r3jSCJCyclin-dependent kinase 22.7.11.220.449
3lfsA07Cyclin-dependent kinase 22.7.11.220.449
3r9dX6BCyclin-dependent kinase 22.7.11.220.449
3rk909ZCyclin-dependent kinase 22.7.11.220.449
4bgh3I6Cyclin-dependent kinase 22.7.11.220.449
3s2pPMUCyclin-dependent kinase 22.7.11.220.447
3rjc06ZCyclin-dependent kinase 22.7.11.220.446
3rahO1ZCyclin-dependent kinase 22.7.11.220.445
4ek610KCyclin-dependent kinase 22.7.11.220.445
2a4lRRCCyclin-dependent kinase 22.7.11.220.444
2r3r6SCCyclin-dependent kinase 22.7.11.220.444
3rni21ZCyclin-dependent kinase 22.7.11.220.443
4fklCK2Cyclin-dependent kinase 22.7.11.220.443
2btsU32Cyclin-dependent kinase 22.7.11.220.442
3qzgX67Cyclin-dependent kinase 22.7.11.220.442
3r73X87Cyclin-dependent kinase 22.7.11.220.442
2b52D42Cyclin-dependent kinase 22.7.11.220.441
2r3kSCQCyclin-dependent kinase 22.7.11.220.441
3qrtX14Cyclin-dependent kinase 22.7.11.220.441
3qxoX65Cyclin-dependent kinase 22.7.11.220.441
1pxlCK4Cyclin-dependent kinase 22.7.11.220.440
3qtuX44Cyclin-dependent kinase 22.7.11.220.440