sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qi2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3qi2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 1.000 | |
| 4g5q | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.568 | |
| 3onw | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.525 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.470 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.460 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.459 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.456 | |
| 1p7c | T5A | Thymidine kinase | / | 0.455 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.451 | |
| 1u0h | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.448 | |
| 1cg1 | IMO | Adenylosuccinate synthetase | / | 0.444 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.444 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.440 |