sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3q2m	CKI	Spectinomycin phosphotransferase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3q2m	CKI	Spectinomycin phosphotransferase	/	1.000
2jc6	QPP	Calcium/calmodulin-dependent protein kinase type 1D	2.7.11.17	0.486
4ajw	VWN	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	2.7.1.153	0.480
4fjy	FJY	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.458
4gi2	NAP	Crotonyl-CoA carboxylase/reductase	/	0.455
1e90	MYC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.450
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.449
3lfc	Z86	Mitogen-activated protein kinase 14	/	0.445
3gcq	1BU	Mitogen-activated protein kinase 14	/	0.441
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.440