sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3pce	3HP	Protocatechuate 3,4-dioxygenase alpha chain	1.13.11.3

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3pce	3HP	Protocatechuate 3,4-dioxygenase alpha chain	1.13.11.3	1.000
3pce	3HP	Protocatechuate 3,4-dioxygenase beta chain	1.13.11.3	1.000
3mfl	DHY	Protocatechuate 3,4-dioxygenase alpha chain	1.13.11.3	0.562
3mfl	DHY	Protocatechuate 3,4-dioxygenase beta chain	1.13.11.3	0.562
3pcg	4HP	Protocatechuate 3,4-dioxygenase alpha chain	1.13.11.3	0.561
3pcg	4HP	Protocatechuate 3,4-dioxygenase beta chain	1.13.11.3	0.561
3pch	CHB	Protocatechuate 3,4-dioxygenase beta chain	1.13.11.3	0.486
3pcn	DHY	Protocatechuate 3,4-dioxygenase alpha chain	1.13.11.3	0.474
3pcn	DHY	Protocatechuate 3,4-dioxygenase beta chain	1.13.11.3	0.474