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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3nup3NUCyclin-dependent kinase 62.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3nup3NUCyclin-dependent kinase 62.7.11.221.000
4ez50RSCyclin-dependent kinase 62.7.11.220.522
2w05FRTCyclin-dependent kinase 22.7.11.220.520
2fvdLIACyclin-dependent kinase 22.7.11.220.500
3nux3NVCyclin-dependent kinase 62.7.11.220.500
3rkb12ZCyclin-dependent kinase 22.7.11.220.492
2vu3LZECyclin-dependent kinase 22.7.11.220.489
4bcmT7ZCyclin-dependent kinase 22.7.11.220.482
3qxpX64Cyclin-dependent kinase 22.7.11.220.479
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.462
1gih1PUCyclin-dependent kinase 22.7.11.220.457
3ezvEZVCyclin-dependent kinase 22.7.11.220.457
2w17I19Cyclin-dependent kinase 22.7.11.220.454
1v1k3FPCyclin-dependent kinase 22.7.11.220.451
2vv9IM9Cyclin-dependent kinase 22.7.11.220.449
4erwSTUCyclin-dependent kinase 22.7.11.220.444
2uzbC75Cyclin-dependent kinase 22.7.11.220.443
1gii1PUCyclin-dependent kinase 22.7.11.220.441
2wouZZFTGF-beta receptor type-12.7.11.300.441