scPDB - Distribution of Cavity Similarity values of 3n5x entry / Site 1

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	1.000
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.728
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.712
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.605
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.587
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.570
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.556
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.547
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.546
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.539
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.537
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.533
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.527
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.520
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.517
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.516
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.514
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.513
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.513
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.511
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.511
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.509
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.508
3n61	H4B	Nitric oxide synthase, brain	1.14.13.39	0.507
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.506
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.505
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.505
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.504
3rqk	X2C	Nitric oxide synthase, brain	1.14.13.39	0.503
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.503
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.501
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.497
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.497
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.496
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.493
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.492
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.490
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.490
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.489
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.486
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.486
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.482
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.482
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.481
4imu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.481
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.480
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.480
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.479
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.479
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.479
4jsg	H4B	Nitric oxide synthase, brain	1.14.13.39	0.478
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.477
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.473
3n5v	XFH	Nitric oxide synthase, brain	1.14.13.39	0.472
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.471
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.468
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.468
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.467
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.466
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.465
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.465
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.463
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.463
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.462
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.462
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.461
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.460
3uft	HW7	Nitric oxide synthase, brain	1.14.13.39	0.459
4fvz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
1om5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.456
3n5v	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
3n5y	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.455
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.455
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.453
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.452
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.451
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
3nln	H4B	Nitric oxide synthase, brain	1.14.13.39	0.449
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.447
3ufq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
3ufs	H4B	Nitric oxide synthase, brain	1.14.13.39	0.446
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445
1k2u	H4B	Nitric oxide synthase, brain	1.14.13.39	0.444
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.444
3jt8	H4B	Nitric oxide synthase, brain	1.14.13.39	0.443
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.443
3uft	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
3n5z	H4B	Nitric oxide synthase, brain	1.14.13.39	0.441
4fw0	H4B	Nitric oxide synthase, brain	1.14.13.39	0.441
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.441
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.440