scPDB - Distribution of Cavity Similarity values of 3n5w entry / Site 1

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	1.000
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.721
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.624
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.605
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.586
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.583
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.581
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.572
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.572
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.561
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.555
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.554
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.550
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.549
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.541
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.540
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.537
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.537
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.536
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.535
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.534
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.531
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.527
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.525
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.524
3rqk	X2C	Nitric oxide synthase, brain	1.14.13.39	0.519
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.518
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.515
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.514
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.513
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.513
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.511
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.508
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.508
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.507
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.506
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.506
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.505
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.504
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.503
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.502
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.500
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.500
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.495
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.493
3uft	HW7	Nitric oxide synthase, brain	1.14.13.39	0.493
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.491
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.487
3n61	H4B	Nitric oxide synthase, brain	1.14.13.39	0.486
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.484
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.483
4jsg	H4B	Nitric oxide synthase, brain	1.14.13.39	0.481
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.480
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.478
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.477
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.476
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.474
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.473
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.473
4fvz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.472
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.472
4imu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.472
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.471
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.470
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.470
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.470
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.469
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.469
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.466
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.464
3nln	H4B	Nitric oxide synthase, brain	1.14.13.39	0.464
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.464
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.463
3rql	H4B	Nitric oxide synthase, brain	1.14.13.39	0.462
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.462
1k2u	H4B	Nitric oxide synthase, brain	1.14.13.39	0.461
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.460
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.460
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.458
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.456
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.456
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.454
4jsi	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3uft	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3nlq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.451
4cx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.451
3b3n	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
3jwu	J11	Nitric oxide synthase, brain	1.14.13.39	0.449
3jx2	H4B	Nitric oxide synthase, brain	1.14.13.39	0.449
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.449
3ufq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.448
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.447
3b3o	H4B	Nitric oxide synthase, brain	1.14.13.39	0.446
3ufp	H4W	Nitric oxide synthase, brain	1.14.13.39	0.446
1om5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445
3nlp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445
1k2t	H4B	Nitric oxide synthase, brain	1.14.13.39	0.443
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.443
3tyl	AXW	Nitric oxide synthase, brain	1.14.13.39	0.442
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.442
3jx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440
3n5v	XFH	Nitric oxide synthase, brain	1.14.13.39	0.440
3n5y	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440
3ufs	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440