sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3lw0	CCX	Insulin-like growth factor 1 receptor	2.7.10.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3lw0	CCX	Insulin-like growth factor 1 receptor	2.7.10.1	1.000
1phg	MYT	Camphor 5-monooxygenase	1.14.15.1	0.470
2w06	FRV	Cyclin-dependent kinase 2	2.7.11.22	0.451
1iwj	CAM	Camphor 5-monooxygenase	1.14.15.1	0.446
4l4d	CAM	Camphor 5-monooxygenase	1.14.15.1	0.444
3cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.443
3oog	YTP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
2cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440
4cp4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440