sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3lsh | FAD | Pyranose 2-oxidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3lsh | FAD | Pyranose 2-oxidase | / | 1.000 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.614 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.575 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.565 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.558 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.484 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.476 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.466 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.456 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.455 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 5a3b | APR | SIR2 family protein | / | 0.447 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.443 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.443 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.443 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.442 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.442 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.440 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.440 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.440 |