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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lfnA27Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lfnA27Cyclin-dependent kinase 22.7.11.221.000
3lfqA28Cyclin-dependent kinase 22.7.11.220.547
4fki09KCyclin-dependent kinase 22.7.11.220.517
1pxmCK5Cyclin-dependent kinase 22.7.11.220.512
3r8lZ30Cyclin-dependent kinase 22.7.11.220.505
2r3jSCJCyclin-dependent kinase 22.7.11.220.500
4fkv61KCyclin-dependent kinase 22.7.11.220.485
2c6o4SPCyclin-dependent kinase 22.7.11.220.483
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.474
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.473
3r83Z14Cyclin-dependent kinase 22.7.11.220.473
1g5sI17Cyclin-dependent kinase 22.7.11.220.469
3r8vZ62Cyclin-dependent kinase 22.7.11.220.468
2a0cCK9Cyclin-dependent kinase 22.7.11.220.466
3rpo24ZCyclin-dependent kinase 22.7.11.220.463
3rahO1ZCyclin-dependent kinase 22.7.11.220.462
1gii1PUCyclin-dependent kinase 22.7.11.220.461
3r7yZ04Cyclin-dependent kinase 22.7.11.220.460
2b52D42Cyclin-dependent kinase 22.7.11.220.457
1pxlCK4Cyclin-dependent kinase 22.7.11.220.456
3qzgX67Cyclin-dependent kinase 22.7.11.220.455
4ek816KCyclin-dependent kinase 22.7.11.220.453
3qu0X40Cyclin-dependent kinase 22.7.11.220.451
4fkj11KCyclin-dependent kinase 22.7.11.220.450
2a4lRRCCyclin-dependent kinase 22.7.11.220.449
3ezvEZVCyclin-dependent kinase 22.7.11.220.449
1pxoCK7Cyclin-dependent kinase 22.7.11.220.448
3rm618ZCyclin-dependent kinase 22.7.11.220.448
3s1h56ZCyclin-dependent kinase 22.7.11.220.444
3rjc06ZCyclin-dependent kinase 22.7.11.220.443
1y91CT9Cyclin-dependent kinase 22.7.11.220.441
2btrU73Cyclin-dependent kinase 22.7.11.220.441
2xmyCDKCyclin-dependent kinase 22.7.11.220.441
4fkq42KCyclin-dependent kinase 22.7.11.220.440