sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3kzo	AN0	N-acetylornithine carbamoyltransferase	2.1.3.9

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3kzo	AN0	N-acetylornithine carbamoyltransferase	2.1.3.9	1.000
3l04	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9	0.689
3l06	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9	0.677
3l05	SN0	N-acetylornithine carbamoyltransferase	2.1.3.9	0.640
3m4n	PA9	N-acetylornithine carbamoyltransferase	2.1.3.9	0.524
3dnt	ATP	Serine/threonine-protein kinase toxin HipA	/	0.457
4dan	2FA	Purine nucleoside phosphorylase DeoD-type	2.4.2.1	0.453
2rd2	QSI	Glutamine--tRNA ligase	6.1.1.18	0.449
3upy	FOM	Oxidoreductase, putative	/	0.449
3ba6	AN2	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.444
1trk	TPP	Transketolase 1	2.2.1.1	0.440
1uae	UD1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.440
4bew	ACP	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.440