sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3h1j | SMA | Cytochrome b |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3h1j | SMA | Cytochrome b | / | 1.000 | |
| 1ppj | SMA | Cytochrome b | / | 0.575 | |
| 1pp9 | SMA | Cytochrome b | / | 0.532 | |
| 2qjy | SMA | Cytochrome b | / | 0.466 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.466 | |
| 1kyo | SMA | Cytochrome b | / | 0.461 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.457 | |
| 3cx5 | SMA | Cytochrome b | / | 0.455 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.455 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.454 | |
| 3cxh | SMA | Cytochrome b | / | 0.451 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.451 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 1kb9 | SMA | Cytochrome b | / | 0.445 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.445 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.442 | |
| 2bxo | OPB | Serum albumin | / | 0.440 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.440 |