Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3gu83GUDeath-associated protein kinase 12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3gu83GUDeath-associated protein kinase 12.7.11.11.000
5av3KMPDeath-associated protein kinase 12.7.11.10.478
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.475
2ckeIQUDeath-associated protein kinase 2/0.459
4qnyANPMitogen activated protein kinase, putative/0.459
4ysjADPCalmodulin-like domain protein kinase/0.458
1jklANPDeath-associated protein kinase 12.7.11.10.455
3gu7ADPDeath-associated protein kinase 12.7.11.10.453
2w4jADPDeath-associated protein kinase 12.7.11.10.452
1ig1ANPDeath-associated protein kinase 12.7.11.10.448
5av2KMPDeath-associated protein kinase 12.7.11.10.447
4jia1K3Tyrosine-protein kinase JAK2/0.445