sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.889
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.848
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.810
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.783
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.724
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.608
1grb	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.557
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.552
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.547
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.541
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.505
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.484
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.468
3dgz	FAD	Thioredoxin reductase 2, mitochondrial	1.8.1.9	0.455