sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3for	ZNP	Thermolysin	3.4.24.27

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3for	ZNP	Thermolysin	3.4.24.27	1.000
4h57	0PJ	Thermolysin	3.4.24.27	0.662
4tln	LNO	Thermolysin	3.4.24.27	0.635
2tmn	0FA	Thermolysin	3.4.24.27	0.627
1qf2	TI3	Thermolysin	3.4.24.27	0.610
4tmn	0PK	Thermolysin	3.4.24.27	0.602
3t8d	UBV	Thermolysin	3.4.24.27	0.598
6tmn	0PI	Thermolysin	3.4.24.27	0.592
3t74	UBY	Thermolysin	3.4.24.27	0.575
3t8h	UBS	Thermolysin	3.4.24.27	0.572
3t8c	UBW	Thermolysin	3.4.24.27	0.560
3f28	S7B	Thermolysin	3.4.24.27	0.557
3t87	UBZ	Thermolysin	3.4.24.27	0.551
3fgd	BYA	Thermolysin	3.4.24.27	0.550
4d9w	X32	Thermolysin	3.4.24.27	0.545
3f2p	S3B	Thermolysin	3.4.24.27	0.508
4ara	C56	Acetylcholinesterase	3.1.1.7	0.452