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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ewyU5PUridine 5'-monophosphate synthase4.1.1.23

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3ewyU5PUridine 5'-monophosphate synthase4.1.1.231.000
3uwqU5POrotidine 5'-phosphate decarboxylase/0.508
2czfXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.489
2gr1FADFerredoxin reductase/0.468
2yyuC5POrotidine 5'-phosphate decarboxylase/0.463
2v8pADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.461
3oibFDAPutative acyl-CoA dehydrogenase/0.455
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.453
4bfzZVZPantothenate kinase2.7.1.330.452
3lm9ADPPutative fructokinase2.7.1.40.451
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
1hdoNAPFlavin reductase (NADPH)/0.449
2briANPUridylate kinase2.7.4.220.449
4h4tFADBiphenyl dioxygenase ferredoxin reductase subunit/0.449
3tjzGNPADP-ribosylation factor 1/0.446
4ewo996Beta-secretase 13.4.23.460.445
3dzvADPHydroxyethylthiazole kinase/0.444
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.444
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.442
4a6cQG9Gag-Pol polyprotein3.4.23.160.441
1h73ANPHomoserine kinase2.7.1.390.440