sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3epx	IMQ	IAG-nucleoside hydrolase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3epx	IMQ	IAG-nucleoside hydrolase	/	1.000
1q23	FUA	Chloramphenicol acetyltransferase	2.3.1.28	0.465
1kic	NOS	IAG-nucleoside hydrolase	/	0.453
2hzq	STR	Apolipoprotein D	/	0.453
3g1r	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.450
3ndj	JHZ	Methyltransferase	/	0.449
3e6e	DCS	Alanine racemase	/	0.448
3dop	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.447
2ejz	SAH	Diphthine synthase	/	0.446
2nmt	MIM	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.444
3u57	DH8	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.441
3u5y	SCG	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.440