sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 1.000 | |
| 2dbq | NAP | Glyoxylate reductase | 1.1.1.26 | 0.552 | |
| 5j23 | A2R | Putative 2-hydroxyacid dehydrogenase | / | 0.495 | |
| 4weq | NAP | NAD-dependent dehydrogenase | / | 0.486 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.480 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.466 | |
| 3kbo | NDP | Glyoxylate/hydroxypyruvate reductase A | / | 0.463 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.452 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.450 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.445 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.440 |