sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2zre | AGS | Protein RecA |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2zre | AGS | Protein RecA | / | 1.000 | |
| 2zrf | DTP | Protein RecA | / | 0.592 | |
| 2zro | ADP | Protein RecA | / | 0.575 | |
| 2zrj | AGS | Protein RecA | / | 0.565 | |
| 1xp8 | AGS | Protein RecA | / | 0.553 | |
| 2zr9 | DTP | Protein RecA | / | 0.521 | |
| 1xmv | ADP | Protein RecA | / | 0.496 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.459 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.446 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 |