sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 1.000 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.461 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 4e2b | FMN | Dehydrogenase | / | 0.448 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.442 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.442 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.440 |