sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2vd4 | P21 | Bifunctional protein GlmU |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2vd4 | P21 | Bifunctional protein GlmU | / | 1.000 | |
| 2w0w | LZS | Bifunctional protein GlmU | / | 0.562 | |
| 2w0v | LZR | Bifunctional protein GlmU | / | 0.559 | |
| 2v0i | UD1 | Bifunctional protein GlmU | / | 0.482 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.457 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 |