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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2v52LABActin, alpha skeletal muscle

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2v52LABActin, alpha skeletal muscle/1.000
2v51LABActin, alpha skeletal muscle/0.590
4b1vLABActin, alpha skeletal muscle/0.573
4gy2LARActin, alpha skeletal muscle/0.494
4b1uLABActin, alpha skeletal muscle/0.490
1rdwLARActin, alpha skeletal muscle/0.486
4b1vATPActin, alpha skeletal muscle/0.478
4h03LARActin, alpha skeletal muscle/0.475
1ijjLARActin, alpha skeletal muscle/0.470
3buzLARActin, alpha skeletal muscle/0.454
3sjhLARActin, alpha skeletal muscle/0.453
2q0uLABActin, alpha skeletal muscle/0.449
4h0yLARActin, alpha skeletal muscle/0.447
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.444