sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2r1n	EPL	Phosphotriesterase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2r1n	EPL	Phosphotriesterase	/	1.000
2d2g	DZZ	Phosphotriesterase	/	0.610
1dpm	EBP	Parathion hydrolase	3.1.8.1	0.552
1ygk	RRC	Pyridoxal kinase	2.7.1.35	0.452
3e33	ED7	Protein farnesyltransferase subunit beta	2.5.1.58	0.448
4g2y	NI5	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.448
2r2l	PB9	Protein farnesyltransferase subunit beta	2.5.1.58	0.446
3q7f	ED2	Uncharacterized protein	/	0.446
4hfr	14M	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.442
1n2g	APC	Pantothenate synthetase	6.3.2.1	0.441