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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q0uLABActin, alpha skeletal muscle

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2q0uLABActin, alpha skeletal muscle/1.000
1rdwLARActin, alpha skeletal muscle/0.630
4b1vLABActin, alpha skeletal muscle/0.625
2v51LABActin, alpha skeletal muscle/0.593
4b1uLABActin, alpha skeletal muscle/0.587
3buzLARActin, alpha skeletal muscle/0.585
4h0yLARActin, alpha skeletal muscle/0.575
1esvLARActin, alpha skeletal muscle/0.570
3sjhLARActin, alpha skeletal muscle/0.567
4h03LARActin, alpha skeletal muscle/0.554
1sqkLARActin, alpha skeletal muscle/0.547
1ijjLARActin, alpha skeletal muscle/0.541
4b1vATPActin, alpha skeletal muscle/0.530
1rfqATPActin, alpha skeletal muscle/0.505
1rfqLARActin, alpha skeletal muscle/0.504
4h0tLARActin, alpha skeletal muscle/0.469
4gy2LARActin, alpha skeletal muscle/0.468
3chwATPMajor actin/0.465
2v52LABActin, alpha skeletal muscle/0.464