sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 1.000 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.714 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.581 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.574 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.566 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.560 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.554 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.547 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.545 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.545 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.541 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.537 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.534 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.531 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.530 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.521 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.516 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.515 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.509 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.505 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.503 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.493 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.462 | |
| 1ppj | ANY | Cytochrome b | / | 0.461 | |
| 2bxq | IMN | Serum albumin | / | 0.460 | |
| 2xvv | 9DN | Serum albumin | / | 0.452 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.449 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 4apu | A2K | Progesterone receptor | / | 0.448 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 1osv | CHC | Bile acid receptor | / | 0.446 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2xvw | 9NR | Serum albumin | / | 0.444 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.442 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.440 |