sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2oz0	FMN	Cytochrome b2, mitochondrial	1.1.2.3

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2oz0	FMN	Cytochrome b2, mitochondrial	1.1.2.3	1.000
1kbj	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.562
1gox	FMN	Peroxisomal (S)-2-hydroxy-acid oxidase	1.1.3.15	0.547
1qcw	FNS	Cytochrome b2, mitochondrial	1.1.2.3	0.529
1kbi	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.515
1fcb	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.511
1szg	FNS	Cytochrome b2, mitochondrial	1.1.2.3	0.509
1szf	FMN	Cytochrome b2, mitochondrial	1.1.2.3	0.504
3giy	FMN	(S)-mandelate dehydrogenase	1.1.99.31	0.487
2nli	FMN	Lactate oxidase	/	0.464
1f8w	FAD	NADH peroxidase	1.11.1.1	0.458
3hf3	FMN	Chromate reductase	/	0.454
1me6	IVS	Plasmepsin-2	3.4.23.39	0.447
5ebu	FMN	Lactate oxidase	/	0.446
2e77	FMN	Lactate oxidase	/	0.440