sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2jlb | UDM | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2jlb | UDM | Uncharacterized protein | / | 1.000 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.461 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.460 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.456 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.455 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.451 | |
| 5cns | CDP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.451 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.448 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.448 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.447 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4k97 | ATP | Cyclic GMP-AMP synthase | / | 0.444 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.444 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.443 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.443 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 |