sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2jkc | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2jkc | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 1.000 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.505 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.466 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 3h18 | PMS | Esterase/lipase | / | 0.454 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.444 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.443 |