Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ijmATPFocal adhesion kinase 12.7.10.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2ijmATPFocal adhesion kinase 12.7.10.21.000
4k8aK8AFocal adhesion kinase 12.7.10.20.517
3pxkPXKFocal adhesion kinase 12.7.10.20.504
2j0lANPFocal adhesion kinase 12.7.10.20.476
2henADPEphrin type-B receptor 22.7.10.10.458
2etm7PYFocal adhesion kinase 12.7.10.20.452
3t8oATPRhodopsin kinase/0.449
2qoqANPEphrin type-A receptor 32.7.10.10.444