sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2gvg	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2gvg	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12	1.000
4m6p	20R	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.534
4m6q	20T	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.524
4lww	LWW	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.519
4kfp	1R7	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.517
2gvj	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.504
2g96	NMN	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.493
4kfo	1QS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.480
4lva	20M	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.477
4kfn	1QR	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.461
4o1d	DGB	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.460
4lvb	20N	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.458
4lts	LTS	Nicotinamide phosphoribosyltransferase	2.4.2.12	0.453