sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2giv | ACO | Histone acetyltransferase KAT8 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 1.000 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.609 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.594 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.591 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.577 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.574 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.574 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.552 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.443 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.442 |