sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2g8a	UMP	Thymidylate synthase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2g8a	UMP	Thymidylate synthase	/	1.000
2g86	UMP	Thymidylate synthase	/	0.595
2g89	UMP	Thymidylate synthase	/	0.581
1tsy	UMP	Thymidylate synthase	/	0.556
2tdm	UMP	Thymidylate synthase	/	0.545
1nje	DCM	Thymidylate synthase	/	0.541
1bpj	UMP	Thymidylate synthase	/	0.521
1tsv	UMP	Thymidylate synthase	/	0.490
1njd	UMP	Thymidylate synthase	/	0.488
1jmf	UMP	Thymidylate synthase	/	0.487
1tsx	UMP	Thymidylate synthase	/	0.476
1jmg	UMP	Thymidylate synthase	/	0.472
2tdd	THF	Thymidylate synthase	/	0.461
1vzb	UMP	Thymidylate synthase	/	0.441