Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2g2hP16Tyrosine-protein kinase ABL12.7.10.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2g2hP16Tyrosine-protein kinase ABL12.7.10.21.000
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.545
1bygSTUTyrosine-protein kinase CSK/0.487
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.487
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.481
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.468
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.457
3ds6A17Mitogen-activated protein kinase 14/0.450
4wa9AXITyrosine-protein kinase ABL12.7.10.20.450
4af3VX6Aurora kinase B2.7.11.10.447
1m52P17Tyrosine-protein kinase ABL12.7.10.20.444
4twpAXITyrosine-protein kinase ABL12.7.10.20.441