sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2ck3	ANP	ATP synthase subunit alpha, mitochondrial

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2ck3	ANP	ATP synthase subunit alpha, mitochondrial	/	1.000
2ck3	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	1.000
1e1q	ANP	ATP synthase subunit alpha, mitochondrial	/	0.522
1e1q	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.522
1nbm	ATP	ATP synthase subunit alpha, mitochondrial	/	0.496
2v7q	ATP	ATP synthase subunit alpha, mitochondrial	/	0.489
2v7q	ATP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.489
2hld	ANP	ATP synthase subunit alpha, mitochondrial	/	0.483
2hld	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.483
1ohh	ANP	ATP synthase subunit alpha, mitochondrial	/	0.459
1ohh	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.459
1h8h	ATP	ATP synthase subunit alpha, mitochondrial	/	0.453
1h8h	ATP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.453
1bmf	ANP	ATP synthase subunit alpha, mitochondrial	/	0.452
1bmf	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.452
3oee	ANP	ATP synthase subunit alpha, mitochondrial	/	0.451
3oee	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.451
1e79	ATP	ATP synthase subunit alpha, mitochondrial	/	0.444
1e79	ATP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.444