sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 1.000 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.516 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.495 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.478 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.471 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.447 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 |