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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2cciATPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2cciATPCyclin-dependent kinase 22.7.11.221.000
4eooATPCyclin-dependent kinase 22.7.11.220.502
2uzbC75Cyclin-dependent kinase 22.7.11.220.470
1fvv107Cyclin-dependent kinase 22.7.11.220.458
3nux3NVCyclin-dependent kinase 62.7.11.220.458
1qmzATPCyclin-dependent kinase 22.7.11.220.456
2w05FRTCyclin-dependent kinase 22.7.11.220.455
4ii5ADPCyclin-dependent kinase 22.7.11.220.455
2vv9IM9Cyclin-dependent kinase 22.7.11.220.450
4fv6E57Mitogen-activated protein kinase 12.7.11.240.450
2cjmATPCyclin-dependent kinase 22.7.11.220.448
3ncz3NCRho-associated protein kinase 12.7.11.10.445
4e6d0NUTyrosine-protein kinase JAK2/0.441
2uzdC85Cyclin-dependent kinase 22.7.11.220.440
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.440
3gu7ADPDeath-associated protein kinase 12.7.11.10.440
3my5RFZCyclin-dependent kinase 22.7.11.220.440
4bcmT7ZCyclin-dependent kinase 22.7.11.220.440