sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2c3u | 2TP | Pyruvate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2c3u | 2TP | Pyruvate synthase | / | 1.000 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.556 | |
| 2pda | TPP | Pyruvate synthase | / | 0.508 | |
| 2uza | HTL | Pyruvate synthase | / | 0.508 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.506 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.496 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.487 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.469 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.466 | |
| 1kek | HTL | Pyruvate synthase | / | 0.465 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.458 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.449 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.443 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.442 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.441 |