Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2b9iADPMitogen-activated protein kinase FUS32.7.11.24

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2b9iADPMitogen-activated protein kinase FUS32.7.11.241.000
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.655
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.565
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.508
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.495
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.488
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.479
4ii5ADPCyclin-dependent kinase 22.7.11.220.473
4qnyANPMitogen activated protein kinase, putative/0.470
1jstATPCyclin-dependent kinase 22.7.11.220.468
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.462
4hge15VTyrosine-protein kinase JAK2/0.461
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.460
4fv9E71Mitogen-activated protein kinase 12.7.11.240.460
4i5cC5ITyrosine-protein kinase JAK1/0.459
4xlvACPInsulin receptor2.7.10.10.458
4i3zADPCyclin-dependent kinase 22.7.11.220.457
1qmzATPCyclin-dependent kinase 22.7.11.220.451
3rak03ZCyclin-dependent kinase 22.7.11.220.449
3ezvEZVCyclin-dependent kinase 22.7.11.220.448
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.447
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.447
3rkb12ZCyclin-dependent kinase 22.7.11.220.447
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.447
2w17I19Cyclin-dependent kinase 22.7.11.220.446
4fk60UJTyrosine-protein kinase JAK1/0.446
4fv6E57Mitogen-activated protein kinase 12.7.11.240.446
4fmqANPMitogen-activated protein kinase 12.7.11.240.443
3zh8C58Protein kinase C iota type2.7.11.130.442
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.440