sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2b96 | ANN | Phospholipase A2 | 3.1.1.4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2b96 | ANN | Phospholipase A2 | 3.1.1.4 | 1.000 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.546 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.517 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.501 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.492 | |
| 3nju | ANN | Acidic phospholipase A2 3 | 3.1.1.4 | 0.490 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.458 | |
| 2e77 | FMN | Lactate oxidase | / | 0.457 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.455 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.455 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.451 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.449 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.449 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.446 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.444 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.444 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 5epe | SAH | Uncharacterized protein | / | 0.443 | |
| 1fdk | GLE | Phospholipase A2 | 3.1.1.4 | 0.442 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.442 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.442 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.441 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.440 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 4kxj | P34 | Nucleoprotein | / | 0.440 |