sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ay5 | IOP | Aromatic-amino-acid aminotransferase | 2.6.1.57 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2ay5 | IOP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 1.000 | |
| 2ay2 | CXP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.668 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.552 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.505 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.504 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.500 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.493 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.492 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.490 | |
| 1x28 | PGU | Aspartate aminotransferase | 2.6.1.1 | 0.489 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.487 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.484 | |
| 1maq | PGU | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.480 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.470 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.466 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.465 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.462 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.459 | |
| 1arg | PPD | Aspartate aminotransferase | 2.6.1.1 | 0.458 | |
| 3ei8 | PL5 | LL-diaminopimelate aminotransferase, chloroplastic | / | 0.455 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.451 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.447 | |
| 3dr4 | G4M | GDP-perosamine synthase | / | 0.447 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.447 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.445 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.443 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 |