sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2ag5	NAD	3-hydroxybutyrate dehydrogenase type 2

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2ag5	NAD	3-hydroxybutyrate dehydrogenase type 2	/	1.000
4c7k	NAP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.454
2dte	NAI	Glucose 1-dehydrogenase related protein	/	0.450
5jla	NAD	Putative short-chain dehydrogenase/reductase	/	0.448
5jsf	NAD	17-beta-hydroxysteroid dehydrogenase 14	1.1.1	0.448
2gdz	NAD	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	1.1.1.141	0.445
4fw8	NAI	3-oxoacyl-(Acyl-carrier-protein) reductase	/	0.444
5js6	NAD	17-beta-hydroxysteroid dehydrogenase 14	1.1.1	0.444
3nug	NAD	Pyridoxal 4-dehydrogenase	1.1.1.107	0.443
3ndr	NAD	Pyridoxal 4-dehydrogenase	1.1.1.107	0.440