sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	1.000
2a59	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.714
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.612
1kyy	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.534
1kyv	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.507
2a58	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.496
1ejb	INJ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.485
4kq6	DLZ	6,7-dimethyl-8-ribityllumazine synthase	/	0.459
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.456
1rvv	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.440