sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2a0w	DIH	Purine nucleoside phosphorylase	2.4.2.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2a0w	DIH	Purine nucleoside phosphorylase	2.4.2.1	1.000
2a0y	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.781
2a0x	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.739
1rsz	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.717
1rt9	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.511
1rr6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.487
3ggs	2FD	Purine nucleoside phosphorylase	2.4.2.1	0.482
3k8q	22A	Purine nucleoside phosphorylase	2.4.2.1	0.475
2oc4	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.451