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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zm4TADExotoxin A2.4.2.36

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1zm4TADExotoxin A2.4.2.361.000
3b82NADExotoxin A2.4.2.360.579
3b8hNADExotoxin A2.4.2.360.577
2zitNADExotoxin A2.4.2.360.554
1xk9P34Exotoxin A2.4.2.360.549
4pnmNU1Tankyrase-22.4.2.300.504
4bj9UHBTankyrase-22.4.2.300.496
3b78NADExotoxin A2.4.2.360.484
1dtpAPUDiphtheria toxin/0.482
3u9y09LTankyrase-22.4.2.300.481
4bjcRPBTankyrase-22.4.2.300.470
4k4eK4ETankyrase-12.4.2.300.464
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.463
4tjy3GNTankyrase-22.4.2.300.459
1ddtAPUDiphtheria toxin/0.458
4pnrG18Tankyrase-22.4.2.300.455
4bjbP34Tankyrase-22.4.2.300.447
4bfsZVSPantothenate kinase2.7.1.330.443